Lubiprostone is a medication acclimated in the
administration of idiopathic abiding constipation. It is a bicyclic blubbery acid
(prostaglandin E1 derivative) which acts by accurately activating ClC-2
chloride channels on the aciculate aspect of gastrointestinal epithelial cells,
bearing a chloride-rich aqueous secretion. These secretions abate the stool,
access motility, and advance ad-lib bowel movements.
Chronic idiopathic ache is about authentic by
exceptional or difficult access of stool. The signs and affection associated
with abiding idiopathic ache may be the aftereffect of aberrant colonic
activity that can adjournment the alteration of belly capacity and impede the
aborticide of belly contents. One access to the analysis of abiding idiopathic
ache is the beard of aqueous into the belly lumen through the activation of
chloride channels in the aciculate film of the gastrointestinal epithelium.
Lubiprostone is a locally acting chloride approach activator that increases belly
chloride and aqueous beard after altering sodium and potassium concentrations
in the serum.
more about:
No comments:
Post a Comment