Sunday, April 16, 2017

What is Cefamandole Nafate?


CAS no.:42540-40-9
Molecular Formula:  C19H18N6NAO6S2
Molecular Weight: 512.50

Cefamandole Nafate is the sodium alkali anatomy of cefamandole formyl ester. Cefamandole nafate is a pro-drug that is anatomize by claret esterases to aftermath cefamandole, a semi-synthetic beta-lactam, second-generation cephalosporin antibacterial with antibacterial activity. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) amid on the close film of the bacterial corpuscle wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains all-important for bacterial corpuscle bank backbone and rigidity. This after-effects in the abrasion of the bacterial corpuscle bank and causes corpuscle lysis.

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