What is trazodone, and how does it work (mechanism of action)?

Trazodone is an articulate antidepressant biologic that affects the actinic messengers (neurotransmitters) aural the academician that fretfulness use to acquaint with (stimulate) anniversary other. The above neurotransmitters are acetylcholine, norepinephrine, dopamine and serotonin. Many experts accept that an alterity a part of the altered neurotransmitters is the could cause of depression. Although the exact apparatus of activity of trazodone is unknown, it apparently improves affection of abasement by inhibiting the uptake of serotonin by fretfulness in the brain. This after-effects in added serotonin to activate added nerves. Trazodone aswell may access anon the activity of serotonin.

Trazodone is chemically different to the careful serotonin reuptake inhibitors (SSRIs), the tricyclic antidepressants (TCAs) or the monoamine oxidase inhibitors (MAO inhibitors). It is chemically accompanying to nefazodone (Serzone) and shares its actions. Trazodone was accustomed by the FDA in 1982.