Cytochrome c Function

Cytochrome c is primarily accepted for its action in the mitochondria as a key actor in the life-supporting action of ATP synthesis. However, if a corpuscle receives an apoptotic stimulus, cytochrome c is appear into the cytosol and triggers programmed corpuscle afterlife through apoptosis.

Cytochrome c is a basic of the electron carriage alternation in mitochondria. The heme accumulation of cytochrome c accepts electrons from the bc1 circuitous and transfers electrons to the circuitous IV. Cytochrome c is aswell complex in admission of apoptosis. Upon absolution of cytochrome c to the cytoplasm, the protein binds apoptotic protease activating factor-1 (Apaf-1).

Cytochrome c can aswell activate several redox reactions such as hydroxylation and ambrosial oxidation, and shows peroxidase action by blaze of assorted electron donors such as 2,2-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS), 2-keto-4-thiomethyl butyric acid and 4-aminoantipyrine.

A bacterial cytochrome c functions as a nitrite reductase.