Epirubicin Description

CAS: 56420-45-2

Molecular Formula:C27H29NO11

Molecular Weight: 543.5193

Epirubicin is a 4'-epi-isomer of the anthracycline antineoplastic antibacterial doxorubicin. Epirubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA archetype and ultimately, interfering with RNA and protein synthesis. This abettor aswell produces baneful free-radical intermediates and interacts with corpuscle film lipids causing lipid peroxidation.

Epirubicin is favoured over doxorubicin, the a lot of known anthracycline, in some chemotherapy regimens as it appears to could cause beneath side-effects. Epirubicin has a altered spatial acclimatization of the hydroxyl accumulation at the 4' carbon of the amoroso – it has the adverse chirality – which may annual for its faster abolishment and bargain toxicity. Epirubicin is primarily used adjoin breast and ovarian cancer, belly cancer, lung blight and lymphomas.Epirubicin is a blight medication that interferes with the advance and advance of blight beef in the body.