CAS
No.: 203923-89-1
Molecular
Formula: C25H28 N2 O4 Si
Molecular
Weight: 448.59
Density:
1.29g/cm3
Boiling
Point: 727.2oC at 760mmHg
Karenitecin,
aswell accepted as Cositecan, is a constructed silicon-containing abettor accompanying
to camptothecin with antineoplastic properties. Karenitecin stabilizes the
cleavable circuitous amid topoisomerase I and DNA, consistent in DNA break and
appropriately triggering apoptosis. Because it is lipophilic, karenitecin
exhibits added tissue assimilation and bio-availability compared to
water-soluble camptothecins.
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